Decreases in TGF-β1 and PDGF levels are associated with echocardiographic changes during adjuvant radiotherapy for breast cancer

BACKGROUND: Radiation-induced heart disease is mainly caused by activation of the fibrotic process. Transforming growth factor-beta 1 (TGF-β1) and platelet-derived growth factor (PDGF) are pro-fibrotic mediators. The aim of our study was to evaluate the behavior of TGF-β1 and PDGF during adjuvant ra...

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Dettagli Bibliografici
Pubblicato in:Radiat Oncol
Autori principali: Aula, Hanna, Skyttä, Tanja, Tuohinen, Suvi, Luukkaala, Tiina, Hämäläinen, Mari, Virtanen, Vesa, Raatikainen, Pekka, Moilanen, Eeva, Kellokumpu-Lehtinen, Pirkko-Liisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194684/
https://ncbi.nlm.nih.gov/pubmed/30340644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-018-1150-7
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