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Modeling WWOX Loss of Function in vivo: What Have We Learned?
The WW domain–containing oxidoreductase (WWOX) gene encompasses a common fragile sites (CFS) known as FRA16D, and is implicated in cancer. WWOX encodes a 46kDa adaptor protein, which contains two N-terminal WW–domains and a catalytic domain at its C–terminus homologous to short–chain dehydrogenase/r...
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| Pubblicato in: | Front Oncol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6194312/ https://ncbi.nlm.nih.gov/pubmed/30370248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00420 |
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