Pharmacokinetic/Pharmacodynamic Integration to Evaluate the Changes in Susceptibility of Actinobacillus pleuropneumoniae After Repeated Administration of Danofloxacin

To evaluate the relationship between pharmacokinetic/pharmacodynamic (PK/PD) parameters and changes in susceptibility and resistance frequency of Actinobacillus pleuropneumoniae CVCC 259, a piglet tissue cage (TC) infection model was established. After A. pleuropneumoniae populations maintained at 1...

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Udgivet i:Front Microbiol
Main Authors: Zhang, Longfei, Kang, Zheng, Yao, Lihua, Gu, Xiaoyan, Huang, Zilong, Cai, Qinren, Shen, Xiangguang, Ding, Huanzhong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194310/
https://ncbi.nlm.nih.gov/pubmed/30369920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02445
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