Innate Immune Detection of Cardioviruses and Viral Disruption of Interferon Signaling

Cardioviruses are members of the Picornaviridae family and infect a variety of mammals, from mice to humans. Replication of cardioviruses produces double stranded RNA that is detected by helicases in the RIG-I-like receptor family and leads to a signaling cascade to produce type I interferon. Like o...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Freundt, Eric C., Drappier, Melissa, Michiels, Thomas
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194174/
https://ncbi.nlm.nih.gov/pubmed/30369921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02448
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