Nuciferine ameliorates hepatic steatosis in high‐fat diet/streptozocin‐induced diabetic mice through a PPARα/PPARγ coactivator‐1α pathway

BACKGROUND AND PURPOSE: Nuciferine, an alkaloid found in Nelumbo nucifera leaves, alleviates dyslipidemia in vivo. However, whether it improves liver injury in diabetic conditions and the underlying mechanism is unclear. The present study aimed to investigate the effects of nuciferine on lipid and g...

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Enregistré dans:
Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Zhang, Chao, Deng, Jianjun, Liu, Dan, Tuo, Xingxia, Xiao, Lei, Lai, Baochang, Yao, Qinyu, Liu, Jia, Yang, Haixia, Wang, Nanping
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193881/
https://ncbi.nlm.nih.gov/pubmed/30129056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14482
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