Nuciferine ameliorates hepatic steatosis in high‐fat diet/streptozocin‐induced diabetic mice through a PPARα/PPARγ coactivator‐1α pathway

BACKGROUND AND PURPOSE: Nuciferine, an alkaloid found in Nelumbo nucifera leaves, alleviates dyslipidemia in vivo. However, whether it improves liver injury in diabetic conditions and the underlying mechanism is unclear. The present study aimed to investigate the effects of nuciferine on lipid and g...

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Bibliographic Details
Published in:Br J Pharmacol
Main Authors: Zhang, Chao, Deng, Jianjun, Liu, Dan, Tuo, Xingxia, Xiao, Lei, Lai, Baochang, Yao, Qinyu, Liu, Jia, Yang, Haixia, Wang, Nanping
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193881/
https://ncbi.nlm.nih.gov/pubmed/30129056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14482
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