Nuciferine ameliorates hepatic steatosis in high‐fat diet/streptozocin‐induced diabetic mice through a PPARα/PPARγ coactivator‐1α pathway

BACKGROUND AND PURPOSE: Nuciferine, an alkaloid found in Nelumbo nucifera leaves, alleviates dyslipidemia in vivo. However, whether it improves liver injury in diabetic conditions and the underlying mechanism is unclear. The present study aimed to investigate the effects of nuciferine on lipid and g...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Zhang, Chao, Deng, Jianjun, Liu, Dan, Tuo, Xingxia, Xiao, Lei, Lai, Baochang, Yao, Qinyu, Liu, Jia, Yang, Haixia, Wang, Nanping
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193881/
https://ncbi.nlm.nih.gov/pubmed/30129056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14482
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