RNA Oncoimmune Phenotyping of HPV-Positive p16-Positive Oropharyngeal Squamous Cell Carcinomas by Nodal Status

IMPORTANCE: Clinical trials that deintensify treatment for patients with suspected human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) use p16 expression to identify HPV-mediated tumors and guide treatment. While p16 staining has a strong correlation with good outcomes,...

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Detalhes bibliográficos
Publicado no:JAMA Otolaryngol Head Neck Surg
Main Authors: Stepp, Wesley H., Farquhar, Douglas, Sheth, Siddharth, Mazul, Angela, Mamdani, Mohammed, Hackman, Trevor G., Hayes, D. Neil, Zevallos, Jose P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193859/
https://ncbi.nlm.nih.gov/pubmed/29710215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoto.2018.0602
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