Running in the wheel: Defining individual severity levels in mice

The fine-scale grading of the severity experienced by animals used in research constitutes a key element of the 3Rs (replace, reduce, and refine) principles and a legal requirement in the European Union Directive 2010/63/EU. Particularly, the exact assessment of all signs of pain, suffering, and dis...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Häger, Christine, Keubler, Lydia M., Talbot, Steven R., Biernot, Svenja, Weegh, Nora, Buchheister, Stephanie, Buettner, Manuela, Glage, Silke, Bleich, André
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Methods and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193607/
https://ncbi.nlm.nih.gov/pubmed/30335759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006159
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