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Biosynthesis of the Thiopeptins and Identification of an F(420)H(2)-Dependent Dehydropiperidine Reductase
Thiopeptins are highly decorated thiopeptide antibiotics similar in structure to thiostrepton A and harbor two unusual features. All thiopeptins contain a thioamide, a rare moiety among natural products, and a subset of thiopeptins present with a piperidine in the core macrocycle rather than the mor...
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| Publicado en: | J Am Chem Soc |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6193465/ https://ncbi.nlm.nih.gov/pubmed/30118217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b04238 |
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