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Loss of a conserved salt bridge in bacterial glycosyl hydrolase BgIM-G1 improves substrate binding in temperate environments
Salt bridges are the strongest electrostatic interactions in proteins. They substantially contribute to a protein’s structural stability. Thus, mutations of salt bridges are typically selected against. Here, we report on the evolutionary loss of a highly conserved salt bridge in the GH1 family glyco...
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| Publicado no: | Commun Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192996/ https://ncbi.nlm.nih.gov/pubmed/30345395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0167-7 |
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