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Heart Specific Knockout of Ndufs4 Ameliorates Ischemia Reperfusion Injury

RATIONALE: Ischemic heart disease (IHD) is a leading cause of mortality. The most effective intervention for IHD is reperfusion, which ironically causes ischemia reperfusion (I/R) injury mainly due to oxidative stress-induced cardiomyocyte death. The exact mechanism and site of reactive oxygen speci...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Zhang, Huiliang, Gong, Guohua, Wang, Pei, Zhang, Zhen, Kolwicz, Stephen C., Rabinovitch, Peter S., Tian, Rong, Wang, Wang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192835/
https://ncbi.nlm.nih.gov/pubmed/30165037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.08.022
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