Outcome of Mismatch Repair‐Deficient Metastatic Colorectal Cancer: The Mayo Clinic Experience

BACKGROUND. Deficiencies in the DNA mismatch repair system cause errors during DNA replication, which in turn give rise to microsatellite instability (MSI). The impact of MSI on survival in metastatic colorectal cancer (mCRC) is unclear. This cohort study aims to investigate the prognostic and predi...

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發表在:Oncologist
Main Authors: Jin, Zhaohui, Sanhueza, Cristobal T., Johnson, Benny, Nagorney, David M., Larson, David W., Mara, Kristin C., Harmsen, William C., Smyrk, Thomas C., Grothey, Axel, Hubbard, Joleen M.
格式: Artigo
語言:Inglês
出版: AlphaMed Press 2018
主題:
Gastrointestinal Cancer
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192616/
https://ncbi.nlm.nih.gov/pubmed/29674439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0289
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