Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor beta Pathway

BACKGROUND & AIMS: Development of hepatocellular carcinoma (HCC) is associated with alterations in the transforming growth factor beta (TGFβ) signaling pathway, which regulates liver inflammation and can have tumor suppressor or promoter activities. Little is known about the roles of specific me...

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Udgivet i:Gastroenterology
Main Authors: Chen, Jian, Zaidi, Sobia, Rao, Shuyun, Chen, Jiun-Sheng, Phan, Liem, Farci, Patrizia, Su, Xiaoping, Shetty, Kirti, White, Jon, Zamboni, Fausto, Wu, Xifeng, Rashid, Asif, Pattabiraman, Nagarajan, Mazumder, Raja, Horvath, Anelia, Wu, Ray-Chang, Li, Shulin, Xiao, Cuiying, Deng, Chu-Xia, Wheeler, David A., Mishra, Bibhuti, Akbani, Rehan, Mishra, Lopa
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192529/
https://ncbi.nlm.nih.gov/pubmed/28918914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.09.007
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