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Control of sensory neuron excitability by serotonin involves 5HT2C receptors and Ca(2+)-activated chloride channels

Serotonin (5HT) is a constituent of the so-called “inflammatory soup” that sensitizes nociceptors during inflammation. Nevertheless, receptors and signaling mechanisms that mediate an excitation of dorsal root ganglion (DRG) neurons by 5HT remained controversial. Therefore, capsaicin-sensitive nocic...

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Vydáno v:Neuropharmacology
Hlavní autoři: Salzer, Isabella, Gantumur, Enkhbileg, Yousuf, Arsalan, Boehm, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192515/
https://ncbi.nlm.nih.gov/pubmed/27511837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.08.006
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