AFF3 upregulation mediates tamoxifen resistance in breast cancers

BACKGROUND: Although tamoxifen is a highly effective drug for treating estrogen receptor–positive (ER(+)) breast cancer, nearly all patients with metastasis with initially responsive tumors eventually relapse, and die from acquired drug resistance. Unfortunately, few molecular mediators of tamoxifen...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Shi, Yawei, Zhao, Yang, Zhang, Yunjian, AiErken, NiJiati, Shao, Nan, Ye, Runyi, Lin, Ying, Wang, Shenming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192118/
https://ncbi.nlm.nih.gov/pubmed/30326937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0928-7
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