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Label-free fluorescence lifetime spectroscopy detects radiation-induced necrotic changes in live brain in real-time

Current clinical imaging modalities do not reliably identify brain tissue regions with necrosis following radiotherapy. This creates challenges for stereotaxic biopsies and surgical-decision making. Time-resolved fluorescence spectroscopy (TRFS) provides a means to rapidly identify necrotic tissue b...

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Dettagli Bibliografici
Pubblicato in:Biomed Opt Express
Autori principali: Hartl, Brad A., Ma, Htet S. W., Sridharan, Shamira, Hansen, Katherine S., Kent, Michael S., Gorin, Fredric, Fragoso, Ruben C., Marcu, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Optical Society of America 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191615/
https://ncbi.nlm.nih.gov/pubmed/30338140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.9.003559
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