A Kirchhoff-Nernst-Planck framework for modeling large scale extracellular electrodiffusion surrounding morphologically detailed neurons

Many pathological conditions, such as seizures, stroke, and spreading depression, are associated with substantial changes in ion concentrations in the extracellular space (ECS) of the brain. An understanding of the mechanisms that govern ECS concentration dynamics may be a prerequisite for understan...

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Publicat a:PLoS Comput Biol
Autors principals: Solbrå, Andreas, Bergersen, Aslak Wigdahl, van den Brink, Jonas, Malthe-Sørenssen, Anders, Einevoll, Gaute T., Halnes, Geir
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191143/
https://ncbi.nlm.nih.gov/pubmed/30286073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006510
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