Dyslipidemia impairs mitochondrial trafficking and function in sensory neurons

Mitochondrial trafficking plays a central role in dorsal root ganglion (DRG) neuronal cell survival and neurotransmission by transporting mitochondria from the neuronal cell body throughout the bundles of DRG axons. In type 2 diabetes (T2DM), dyslipidemia and hyperglycemia damage DRG neurons and ind...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Rumora, Amy E., Lentz, Stephen I., Hinder, Lucy M., Jackson, Samuel W., Valesano, Andrew, Levinson, Gideon E., Feldman, Eva L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191072/
https://ncbi.nlm.nih.gov/pubmed/28904018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700206R
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