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Overexpression of Chicken IRF7 Increased Viral Replication and Programmed Cell Death to the Avian Influenza Virus Infection Through TGF-Beta/FoxO Signaling Axis in DF-1

During mammalian viral infections, interferon regulatory factor 7 (IRF7) partners with IRF3 to regulate the type I interferon response. In chickens, however, it is still unclear how IRF7 functions in the host innate immune response, especially given that IRF3 is absent. To further elucidate the func...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Kim, Tae Hyun, Zhou, Huaijun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190866/
https://ncbi.nlm.nih.gov/pubmed/30356848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00415
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