Toll-Like Receptor 4 (TLR-4) Pathway Promotes Pulmonary Inflammation in Chronic Intermittent Hypoxia-Induced Obstructive Sleep Apnea

BACKGROUND: Studies have shown that intermittent hypoxia mimics obstructive sleep apnea in causing pulmonary inflammation, but the mechanism is not yet clear.TLR-4 is a recognized proinflammatory factor, so the purpose of this study was to assess the function of TLR-4 in pulmonary inflammation induc...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Yang, Jiao-Jiao, Wang, Shu-Juan, Gao, Xiao-Ling, Wang, Bei, Dong, Yan-Ting, Bai, Yang, Chen, Yan, Gong, Jian-Nan, Huang, Ya-Qiong, An, Dong-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Animal Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190728/
https://ncbi.nlm.nih.gov/pubmed/30293084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910632
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