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Hypothalamic PDE3B deficiency alters body weight and glucose homeostasis in mouse

Pharmacological studies have suggested hypothalamic phosphodiesterase-3B to mediate leptin and insulin action in regulation of energy homeostasis. Whereas Pde3b-null mice show altered energy homeostasis, it is unknown whether this is due to ablation of Pde3b in the hypothalamus. Thus to address the...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Sahu, Maitrayee, Anamthathmakula, Prashanth, Sahu, Abhiram
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190684/
https://ncbi.nlm.nih.gov/pubmed/30307157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0304
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