Novel vancomycin–peptide conjugate as potent antibacterial agent against vancomycin-resistant Staphylococcus aureus

BACKGROUND: Increase in vancomycin (Van)-resistant bacterial strains including vancomycin-resistant Staphylococcus aureus (VRSA) and lack of new effective antibiotics have become a formidable health problem. MATERIALS AND METHODS: We designed a new conjugate composed of Van and a peptide Hecate (Hec...

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Bibliografische gegevens
Gepubliceerd in:Infect Drug Resist
Hoofdauteurs: Jelinkova, Pavlina, Splichal, Zbynek, Jimenez, Ana Maria Jimenez, Haddad, Yazan, Mazumdar, Aninda, Sur, Vishma Pratap, Milosavljevic, Vedran, Kopel, Pavel, Buchtelova, Hana, Guran, Roman, Zitka, Ondrej, Richtera, Lukas, Hegerova, Dagmar, Heger, Zbynek, Moulick, Amitava, Adam, Vojtech
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2018
Onderwerpen:
Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190637/
https://ncbi.nlm.nih.gov/pubmed/30349337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S160975
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