Novel vancomycin–peptide conjugate as potent antibacterial agent against vancomycin-resistant Staphylococcus aureus

BACKGROUND: Increase in vancomycin (Van)-resistant bacterial strains including vancomycin-resistant Staphylococcus aureus (VRSA) and lack of new effective antibiotics have become a formidable health problem. MATERIALS AND METHODS: We designed a new conjugate composed of Van and a peptide Hecate (Hec...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: Jelinkova, Pavlina, Splichal, Zbynek, Jimenez, Ana Maria Jimenez, Haddad, Yazan, Mazumdar, Aninda, Sur, Vishma Pratap, Milosavljevic, Vedran, Kopel, Pavel, Buchtelova, Hana, Guran, Roman, Zitka, Ondrej, Richtera, Lukas, Hegerova, Dagmar, Heger, Zbynek, Moulick, Amitava, Adam, Vojtech
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190637/
https://ncbi.nlm.nih.gov/pubmed/30349337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S160975
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