Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma

PURPOSE: We investigated the effect of carbonic anhydrase IX (CA IX) inhibitor under hypoxia and normoxia in SaOS2 human osteosarcoma cell line. We also evaluated the expression of CA IX in 27 patients diagnosed with osteosarcoma. MATERIALS AND METHODS: CA IX expression in SaOS2 cells cultured under...

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Foilsithe in:Onco Targets Ther
Main Authors: Okuno, Kazuma, Matsubara, Takao, Nakamura, Tomoki, Iino, Takahiro, Kakimoto, Takuya, Asanuma, Kunihiro, Matsumine, Akihiko, Sudo, Akihiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2018
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190629/
https://ncbi.nlm.nih.gov/pubmed/30349321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S177605
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