Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma

PURPOSE: We investigated the effect of carbonic anhydrase IX (CA IX) inhibitor under hypoxia and normoxia in SaOS2 human osteosarcoma cell line. We also evaluated the expression of CA IX in 27 patients diagnosed with osteosarcoma. MATERIALS AND METHODS: CA IX expression in SaOS2 cells cultured under...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Okuno, Kazuma, Matsubara, Takao, Nakamura, Tomoki, Iino, Takahiro, Kakimoto, Takuya, Asanuma, Kunihiro, Matsumine, Akihiko, Sudo, Akihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190629/
https://ncbi.nlm.nih.gov/pubmed/30349321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S177605
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