Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress

Albuminuria is an early marker of renovascular damage associated to an increase in oxidative stress. The Munich Wistar Frömter (MWF) rat is a model of chronic kidney disease (CKD), which exhibits endothelial dysfunction associated to low nitric oxide availability. We hypothesize that the new highly...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: González-Blázquez, Raquel, Somoza, Beatriz, Gil-Ortega, Marta, Martín Ramos, Miriam, Ramiro-Cortijo, David, Vega-Martín, Elena, Schulz, Angela, Ruilope, Luis Miguel, Kolkhof, Peter, Kreutz, Reinhold, Fernández-Alfonso, María S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189469/
https://ncbi.nlm.nih.gov/pubmed/30356804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01131
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