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Development of Adjuvant-Free Bivalent Food Poisoning Vaccine by Augmenting the Antigenicity of Clostridium perfringens Enterotoxin

Clostridium perfringens enterotoxin (CPE) is a common cause of food poisoning and hyperkalemia-associated death. Previously, we reported that fusion of pneumococcal surface protein A (PspA) to C-terminal fragment of CPE (C-CPE) efficiently bound mucosal epithelium so that PspA-specific immune respon...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Suzuki, Hidehiko, Hosomi, Koji, Nasu, Ayaka, Kondoh, Masuo, Kunisawa, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189403/
https://ncbi.nlm.nih.gov/pubmed/30356722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02320
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