Including Phenotypic Causal Networks in Genome-Wide Association Studies Using Mixed Effects Structural Equation Models

Network based statistical models accounting for putative causal relationships among multiple phenotypes can be used to infer single-nucleotide polymorphism (SNP) effect which transmitting through a given causal path in genome-wide association studies (GWAS). In GWAS with multiple phenotypes, reconst...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Momen, Mehdi, Ayatollahi Mehrgardi, Ahmad, Amiri Roudbar, Mahmoud, Kranis, Andreas, Mercuri Pinto, Renan, Valente, Bruno D., Morota, Gota, Rosa, Guilherme J. M., Gianola, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189326/
https://ncbi.nlm.nih.gov/pubmed/30356716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00455
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