Culture-Negative Early-Onset Neonatal Sepsis — At the Crossroad Between Efficient Sepsis Care and Antimicrobial Stewardship

Sepsis is a leading cause of mortality and morbidity in neonates. Presenting clinical symptoms are unspecific. Sensitivity and positive predictive value of biomarkers at onset of symptoms are suboptimal. Clinical suspicion therefore frequently leads to empirical antibiotic therapy in uninfected infa...

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Udgivet i:Front Pediatr
Main Authors: Klingenberg, Claus, Kornelisse, René F., Buonocore, Giuseppe, Maier, Rolf F., Stocker, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pediatrics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189301/
https://ncbi.nlm.nih.gov/pubmed/30356671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2018.00285
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