Whole-Genome Linkage Scan Combined With Exome Sequencing Identifies Novel Candidate Genes for Carotid Intima-Media Thickness

Carotid intima-media thickness (cIMT) is an established heritable marker for subclinical atherosclerosis. In this study, we aim to identify rare variants with large effects driving differences in cIMT by performing genome-wide linkage analysis of individuals in the extremes of cIMT trait distributio...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Vojinovic, Dina, Kavousi, Maryam, Ghanbari, Mohsen, Brouwer, Rutger W. W., van Rooij, Jeroen G. J., van den Hout, Mirjam C. G. N., Kraaij, Robert, van Ijcken, Wilfred F. J., Uitterlinden, Andre G., van Duijn, Cornelia M., Amin, Najaf
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Genetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189289/
https://ncbi.nlm.nih.gov/pubmed/30356672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00420
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