Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer with genetic susceptibility loci identified in recent genome-wide association studies (GWAS). Transcriptome-wide association studies (TWAS) using imputed gene expression levels can identify additional gene-level associations. Here we i...

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Udgivet i:Nat Commun
Main Authors: Ioannidis, Nilah M., Wang, Wei, Furlotte, Nicholas A., Hinds, David A., Bustamante, Carlos D., Jorgenson, Eric, Asgari, Maryam M., Whittemore, Alice S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189170/
https://ncbi.nlm.nih.gov/pubmed/30323283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06149-6
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