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Application of the parametric bootstrap for gene-set analysis of gene–environment interactions

Testing for gene–environment (GE) interactions in a gene-set defined by a biological pathway can help us understand the interplay between genes and environments and provide insight into disease etiology. A self-contained gene-set analysis can be performed by combining gene-level p-values using appro...

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Publicat a:Eur J Hum Genet
Autors principals: Coombes, Brandon J., Biernacka, Joanna M.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189148/
https://ncbi.nlm.nih.gov/pubmed/30089830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-018-0236-x
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