BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts

“BRCAX” refers breast cancers occurring in women with a family history predictive of being a BRCA1/2 mutation carrier, but BRCA1/2 genetic screening has failed to find causal mutations. In this study, we report the findings of the genetic architecture of BRCAX with novel and redefined candidate loci...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Joo-Yeon, Kim, Jisun, Kim, Sung-Won, Park, Sue K., Ahn, Sei Hyun, Lee, Min Hyuk, Suh, Young Jin, Noh, Dong-Young, Son, Byung Ho, Cho, Young Up, Lee, Sae Byul, Lee, Jong Won, Hopper, John L., Sung, Joohon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189145/
https://ncbi.nlm.nih.gov/pubmed/30323354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31859-8
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