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Hydrogen Sulfide Promotes Bone Homeostasis by Balancing Inflammatory Cytokine Signaling in CBS-Deficient Mice through an Epigenetic Mechanism

Previously, we have shown hyperhomocysteinemia (HHcy) to have a detrimental effect on bone remodeling, which is associated with osteoporosis. During transsulfuration, Hcy is metabolized into hydrogen sulfide (H(2)S), a gasotransmitter molecule known to regulate bone formation. Therefore, in the pres...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Behera, Jyotirmaya, Kelly, Kimberly E., Voor, Michael J., Metreveli, Naira, Tyagi, Suresh C., Tyagi, Neetu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189133/
https://ncbi.nlm.nih.gov/pubmed/30323246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33149-9
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