A single-dose live-attenuated Zika virus vaccine with controlled infection rounds that protects against vertical transmission

Zika virus (ZIKV) infection of the mother during pregnancy causes devastating Zika congenital syndrome in the offspring. A ZIKV vaccine with optimal safety and immunogenicity for use in pregnant women is critically needed. Towards this goal, we have developed a singledose live-attenuated vaccine can...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Xie, Xuping, Kum, Dieudonné B., Xia, Hongjie, Luo, Huanle, Shan, Chao, Zou, Jing, Muruato, Antonio E., Medeiros, Daniele B. A., Nunes, Bruno T. D., Dallmeier, Kai, Rossi, Shannan L., Weaver, Scott C., Neyts, Johan, Wang, Tian, Vasconcelos, Pedro F. C., Shi, Pei-Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188708/
https://ncbi.nlm.nih.gov/pubmed/30308155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.09.008
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