Ca(2+) Signals in Astrocytes Facilitate Spread of Epileptiform Activity

Epileptic seizures are associated with increased astrocytic Ca(2+) signaling, but the fine spatiotemporal kinetics of the ictal astrocyte–neuron interplay remains elusive. By using 2-photon imaging of awake head-fixed mice with chronic hippocampal windows we demonstrate that astrocytic Ca(2+) signal...

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Publicado en:Cereb Cortex
Autores principales: Heuser, Kjell, Nome, Cecilie G, Pettersen, Klas H, Åbjørsbråten, Knut S, Jensen, Vidar, Tang, Wannan, Sprengel, Rolf, Taubøll, Erik, Nagelhus, Erlend A, Enger, Rune
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188565/
https://ncbi.nlm.nih.gov/pubmed/30169757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhy196
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