Candida albicans secreted aspartic proteases 4–6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism

Systemic infection by the pathogenic yeast Candida albicans produces high mortality in immune-compromised people. Such infection starts with the penetration of the organism at the mucosal surfaces, facilitated by the secreted aspartic proteases (Saps) 4, 5, and 6. The functional mechanism of these v...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Wu, Hao, Downs, Deborah, Ghosh, Koena, Ghosh, Arun K., Staib, Peter, Monod, Michel, Tang, Jordan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2013
Schlagworte:
Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188231/
https://ncbi.nlm.nih.gov/pubmed/23430844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-214353
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