Cardiac acetylcholine inhibits ventricular remodeling and dysfunction under pathologic conditions

Autonomic dysfunction is a characteristic of cardiac disease and decreased vagal activity is observed in heart failure. Rodent cardiomyocytes produce de novo ACh, which is critical in maintaining cardiac homeostasis. We report that this nonneuronal cholinergic system is also found in human cardiomyo...

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Publicat a:FASEB J
Autors principals: Roy, Ashbeel, Dakroub, Mouhamed, Tezini, Geisa C. S. V., Liu, Yin, Guatimosim, Silvia, Feng, Qingping, Salgado, Helio C., Prado, Vania F., Prado, Marco A. M., Gros, Robert
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2016
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188225/
https://ncbi.nlm.nih.gov/pubmed/26481308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-277046
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