One Step Beyond: Design of Substrates Spanning Primed Positions of Zika Virus NS2B-NS3 Protease

[Image: see text] Although the mosquito-borne Zika virus was discovered in the late 1940s of the 20th century, for years it was neglected, as the disease in humans was rare and relatively mild. Viral NS2B-NS3 protease is essential for virus replication, and except for maturation of viral proteins, i...

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Vydáno v:ACS Med Chem Lett
Hlavní autoři: Gruba, Natalia, Martinez, Jose Ignacio Rodriguez, Grzywa, Renata, Wysocka, Magdalena, Skoreński, Marcin, Dabrowska, Agnieszka, Łęcka, Maria, Suder, Piotr, Sieńczyk, Marcin, Pyrc, Krzysztof, Lesner, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2018
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187398/
https://ncbi.nlm.nih.gov/pubmed/30344911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00316
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