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CPEB2‐dependent translation of long 3′‐UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue

Expression of mitochondrial proton transporter uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) is essential for mammalian thermogenesis. While human UCP1 mRNA exists in a long form only, alternative polyadenylation creates two different isoforms in mice with 10% of UCP1 mRNA found in the l...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Chen, Hui‐Feng, Hsu, Chen‐Ming, Huang, Yi‐Shuian
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187220/
https://ncbi.nlm.nih.gov/pubmed/30177570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899071
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