טוען...
PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice
PAX5 is a well-known haploinsufficient tumor suppressor gene in human B-cell precursor acute lymphoblastic leukemia (B-ALL) and is involved in various chromosomal translocations that fuse a part of PAX5 with other partners. However, the role of PAX5 fusion proteins in B-ALL initiation and transforma...
שמור ב:
הוצא לאור ב: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
National Academy of Sciences
2018
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187160/ https://ncbi.nlm.nih.gov/pubmed/30257940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721678115 |
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