Optimal protection against Salmonella infection requires noncirculating memory

While CD4 Th1 cells are required for resistance to intramacrophage infections, adoptive transfer of Th1 cells is insufficient to protect against Salmonella infection. Using an epitope-tagged vaccine strain of Salmonella, we found that effective protection correlated with expanded Salmonella-specific...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Benoun, Joseph M., Peres, Newton G., Wang, Nancy, Pham, Oanh H., Rudisill, Victoria L., Fogassy, Zachary N., Whitney, Paul G., Fernandez-Ruiz, Daniel, Gebhardt, Thomas, Pham, Quynh-Mai, Puddington, Lynn, Bedoui, Sammy, Strugnell, Richard A., McSorley, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187142/
https://ncbi.nlm.nih.gov/pubmed/30254173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808339115
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