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Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay

Mammalian embryos are surrounded by an acellular shell, the zona pellucida. Hatching out of the zona is crucial for implantation and continued development of the embryo. Clinically, problems in hatching can contribute to failure in assisted reproductive intervention. Although hatching is fundamental...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Leonavicius, Karolis, Royer, Christophe, Preece, Chris, Davies, Benjamin, Biggins, John S., Srinivas, Shankar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187134/
https://ncbi.nlm.nih.gov/pubmed/30232257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719930115
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