Crimping-induced structural gradients explain the lasting strength of poly l-lactide bioresorbable vascular scaffolds during hydrolysis

Biodegradable polymers open the way to treatment of heart disease using transient implants (bioresorbable vascular scaffolds, BVSs) that overcome the most serious complication associated with permanent metal stents—late stent thrombosis. Here, we address the long-standing paradox that the clinically...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ramachandran, Karthik, Di Luccio, Tiziana, Ailianou, Artemis, Kossuth, Mary Beth, Oberhauser, James P., Kornfield, Julia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
Schlagworte:
Physical Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187115/
https://ncbi.nlm.nih.gov/pubmed/30224483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807347115
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