Spinal dorsal horn astrocytes release GABA in response to synaptic activation

KEY POINTS: GABA is an essential molecule for sensory information processing. It is usually assumed to be released by neurons. Here we show that in the dorsal horn of the spinal cord, astrocytes respond to glutamate by releasing GABA. Our findings suggest a novel role for astrocytes in somatosensory...

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Udgivet i:J Physiol
Main Authors: Christensen, Rasmus Kordt, Delgado‐Lezama, Rodolfo, Russo, Raúl E., Lind, Barbara Lykke, Alcocer, Emanuel Loeza, Rath, Martin Fredensborg, Fabbiani, Gabriela, Schmitt, Nicole, Lauritzen, Martin, Petersen, Anders Victor, Carlsen, Eva Meier, Perrier, Jean‐François
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187042/
https://ncbi.nlm.nih.gov/pubmed/30079574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276562
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