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Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma

Introduction: Temozolomide (TMZ) is part of the standard of care for treating glioblastoma multiforme (GBM), an aggressive primary brain tumor. New approaches are needed to enhance therapeutic efficacy and reduce toxicity. GBM tumor cells are dependent on glucose and glutamine while relying heavily...

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Publié dans:Front Nutr
Auteurs principaux: Augur, Zachary M., Doyle, Catherine M., Li, Mingyi, Mukherjee, Purna, Seyfried, Thomas N.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186985/
https://ncbi.nlm.nih.gov/pubmed/30349820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnut.2018.00091
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