Insights into the antibacterial mechanism of PEGylated nano-bacitracin A against Streptococcus pneumonia: both penicillin-sensitive and penicillin-resistant strains

BACKGROUND: Multidrug-resistant (MDR) Streptococcus pneumonia constitute a major worldwide public health concern. MATERIALS AND METHODS: In our preliminary study, PEGylated nano-self-assemblies of bacitracin A (PEGylated Nano-BA(12K)) showed strong antibacterial potency against reference S. pneumoni...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Hong, Wei, Liu, Lipeng, Zhang, Zehui, Zhao, Yining, Zhang, Dexian, Liu, Mingchun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186892/
https://ncbi.nlm.nih.gov/pubmed/30349251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S178596
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