Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes

The postnatal mammary gland undergoes repeated cycles of proliferation and cell death, most notably when the fully differentiated (lactating) gland dedifferentiates to a prelactation state. Accumulation of milk proteins in the secretory epithelium creates the stress signal that triggers this process...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Discov
Prif Awduron: Wärri, Anni, Cook, Katherine L., Hu, Rong, Jin, Lu, Zwart, Alan, Soto-Pantoja, David R., Liu, Jie, Finkel, Toren, Clarke, Robert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186758/
https://ncbi.nlm.nih.gov/pubmed/30345078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0105-y
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg