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Effects of rheumatoid arthritis associated transcriptional changes on osteoclast differentiation network in the synovium

BACKGROUND: Osteoclast differentiation in the inflamed synovium of rheumatoid arthritis (RA) affected joints leads to the formation of bone lesions. Reconstruction and analysis of protein interaction networks underlying specific disease phenotypes are essential for designing therapeutic intervention...

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Pubblicato in:PeerJ
Autori principali: Harshan, Shilpa, Dey, Poulami, Ragunathan, Srivatsan
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186409/
https://ncbi.nlm.nih.gov/pubmed/30324023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5743
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