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The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen Species

BACKGROUND: Mitochondrial dynamics (mtDYN) has been proposed as a bridge between mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis of type 2 diabetes (T2D). Our previous study has identified that mitochondrial DNA (mtDNA) haplogroup B4 is a T2D-susceptible...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oxid Med Cell Longev
Main Authors: Lin, Hung-Yu, Weng, Shao-Wen, Chang, Yen-Hsiang, Su, Yu-Jih, Chang, Chih-Min, Tsai, Chia-Jen, Shen, Feng-Chih, Chuang, Jiin-Haur, Lin, Tsu-Kung, Liou, Chia-Wei, Lin, Ching-Yi, Wang, Pei-Wen
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186363/
https://ncbi.nlm.nih.gov/pubmed/30363990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7514383
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