Genetic polymorphism and natural selection of circumsporozoite surface protein in Plasmodium falciparum field isolates from Myanmar

BACKGROUND: Plasmodium falciparum circumsporozoite protein (PfCSP) is one of the most extensively studied malaria vaccine candidates, but the genetic polymorphism of PfCSP within and among the global P. falciparum population raises concerns regarding the efficacy of a PfCSP-based vaccine efficacy. I...

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Dettagli Bibliografici
Pubblicato in:Malar J
Autori principali: Lê, Hương Giang, Kang, Jung-Mi, Moe, Mya, Jun, Hojong, Thái, Thị Lam, Lee, Jinyoung, Myint, Moe Kyaw, Lin, Khin, Sohn, Woon-Mok, Shin, Ho-Joon, Kim, Tong-Soo, Na, Byoung-Kuk
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186114/
https://ncbi.nlm.nih.gov/pubmed/30314440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2513-0
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