p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification

BACKGROUND: Malignant pleural mesothelioma (MPM) is an orphan disease that is difficult to treat using traditional chemotherapy, an approach which has been effective in other types of cancer. Most chemotherapeutics cause DNA damage leading to cell death. Recent discoveries have highlighted a potenti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Tian, Kun, Bakker, Emyr, Hussain, Michelle, Guazzelli, Alice, Alhebshi, Hasen, Meysami, Parisa, Demonacos, Constantinos, Schwartz, Jean-Marc, Mutti, Luciano, Krstic-Demonacos, Marija
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186085/
https://ncbi.nlm.nih.gov/pubmed/30316293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1650-0
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