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Bioenergetics in fibroblasts of patients with Huntington disease are associated with age at onset

OBJECTIVE: We aimed to assess whether differences in energy metabolism in fibroblast cell lines derived from patients with Huntington disease were associated with age at onset independent of the cytosine-adenine-guanine (CAG) repeat number in the mutant allele. METHODS: For this study, we selected 9...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neurol Genet
मुख्य लेखकों: Gardiner, Sarah L., Milanese, Chiara, Boogaard, Merel W., Buijsen, Ronald A.M., Hogenboom, Marye, Roos, Raymund A.C., Mastroberardino, Pier G., van Roon-Mom, Willeke M.C., Aziz, N. Ahmad
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Wolters Kluwer 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186024/
https://ncbi.nlm.nih.gov/pubmed/30338295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000275
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